I’m on Methotrexate and it is honestly life changing. It can have vile side effects but so far I’ve not had any, it will depend on the dosage. I’m not sure how it is for Osteoarthritis, so would definitely rec. a second dr opinion and get to the bottom of it. Ibuprofen doesn’t even touch it, I’d be pestering the Doctor for a proper arthritis consultation and some better pain meds in the meantime.